Rolla is a city in and the county seat of Phelps County, Missouri, United States. The population in the 2010 United States Census was 19,559. Rolla is located approximately midway between St. Louis and Springfield along I-44. The Rolla, Mo Micropolitan Statistical area consists of Phelps County, Missouri.It is the home of the Missouri University of Science and Technology, well known, both nationally and internationally, for its many engineering departments and computer science department.The headquarters of the Mark Twain National Forest is located in Rolla. In addition, this is part of the Ozark Highlands American Viticultural Area, with vineyards established first by Italian immigrants to the area.